Gentoo Linux is an open source operating system built on top of the Linux kernel and based on the Portage package management system.
KDE is mainly known for producing the KDE Desktop Environment (used in Kubuntu) for Linux.
Joomla is one of the leading open-source Content Management Systems. With a userbase of over 400,000, they use phpBB as a reliable platform for support.
OpenOffice.org offers a free and fully-featured office suite which meets the needs of the common consumer all the way up to large enterprises.
Discussion board for the massively popular xkcd web comic. Covering everything from Maths and Science to Logic Puzzles and Forum Games. Over 100k members and 2.4 Million posts.
Boasting almost 14 million posts, Ars Technica is one of the biggest and oldest technical forums still operating today. They use phpBB to power their forums and comment system.