Discussion board for the massively popular xkcd web comic. Covering everything from Maths and Science to Logic Puzzles and Forum Games. Over 100k members and 2.4 Million posts.
Official Support Forum for Debian, the kernel-based open source operating system. phpBB provides a solid platform for support and discussion.
The Raspberry Pi is a cheap, credit-card sized computer. The official website uses phpBB for their discussion forums.
Inspired by Max Berry's book, Jennifer Government, NationStates is one of the most popular online simulation games. The forum boasts over 5 million posts and 200,000 users.
Conquer Club is an online multiplayer world domination game. The discussion forum is host to over 500,000 members and 2.8 million posts.
The VideoLAN project produces the extremely popular VLC media player software. Their forums provide support for users of the software as well as the development community.