Discussion board for the massively popular xkcd web comic. Covering everything from Maths and Science to Logic Puzzles and Forum Games. Over 100k members and 2.4 Million posts.
Joomla is one of the leading open-source Content Management Systems. With a userbase of over 400,000, they use phpBB as a reliable platform for support.
KDE is mainly known for producing the KDE Desktop Environment (used in Kubuntu) for Linux.
Developed by Focus Home Interactive, Cities XL 2011 is a city simulation game. Their community forums are powered by phpBB.
Inspired by Max Berry's book, Jennifer Government, NationStates is one of the most popular online simulation games. The forum boasts over 5 million posts and 200,000 users.
Zend Technologies is one of the largest and most popular companies producing a wide variety of tools and frameworks for PHP. Their community forums rely on phpBB.