OpenOffice.org offers a free and fully-featured office suite which meets the needs of the common consumer all the way up to large enterprises.
Discussion board for the massively popular xkcd web comic. Covering everything from Maths and Science to Logic Puzzles and Forum Games. Over 100k members and 2.4 Million posts.
Inspired by Max Berry's book, Jennifer Government, NationStates is one of the most popular online simulation games. The forum boasts over 5 million posts and 200,000 users.
Pixelmator is a popular commercial image editing software for Mac OS X users.
Avant Browser is a fast and user friendly browser which uses Microsoft's Trident rendering engine. The browser has been downloaded over 22 million times.
Hugely popular Mozilla community providing support for Firefox, Thunderbird, Seamonkey and other well known Mozilla products. Over 350k members and 4 Million posts.