It is the Italian Community for Ubuntu, a popular open source community operating system based upon the the Debian Linux Distribution.
Info-Mac is a community dating back to 1984 as a mailing list and was the first online community for Apple's Macintosh computer. All of their content was converted to phpBB in 2007.
Discussion board for the massively popular xkcd web comic. Covering everything from Maths and Science to Logic Puzzles and Forum Games. Over 100k members and 2.4 Million posts.
Professional online broker and trading community.
The VideoLAN project produces the extremely popular VLC media player software. Their forums provide support for users of the software as well as the development community.
Inspired by Max Berry's book, Jennifer Government, NationStates is one of the most popular online simulation games. The forum boasts over 5 million posts and 200,000 users.