Joomla is one of the leading open-source Content Management Systems. With a userbase of over 400,000, they use phpBB as a reliable platform for support.
OpenCart is popular, powerful, and easy to use shopping cart software. Their healthy community forums are powered by phpBB.
Info-Mac is a community dating back to 1984 as a mailing list and was the first online community for Apple's Macintosh computer. All of their content was converted to phpBB in 2007.
Independent site for Dutch horse lovers. With over 280,000 members and 95 million posts, Bokt.nl is widely acclaimed as one of the largest boards powered by phpBB.
KDE is mainly known for producing the KDE Desktop Environment (used in Kubuntu) for Linux.
Discussion board for the massively popular xkcd web comic. Covering everything from Maths and Science to Logic Puzzles and Forum Games. Over 100k members and 2.4 Million posts.