Gentoo Linux is an open source operating system built on top of the Linux kernel and based on the Portage package management system.
Discussion forum for the massively popular American animated sitcom. Powered by phpBB.
Discussion board for the massively popular xkcd web comic. Covering everything from Maths and Science to Logic Puzzles and Forum Games. Over 100k members and 2.4 Million posts.
KDE is mainly known for producing the KDE Desktop Environment (used in Kubuntu) for Linux.
Info-Mac is a community dating back to 1984 as a mailing list and was the first online community for Apple's Macintosh computer. All of their content was converted to phpBB in 2007.
Boasting almost 14 million posts, Ars Technica is one of the biggest and oldest technical forums still operating today. They use phpBB to power their forums and comment system.